Junk Science – Junk Ethics

In December 2012 ‘Unique immunologic patterns in fibromyalgia’ was published as Behm et al. BMC Clinical Pathology 2012, 12:25 http://www.biomedcentral.com/1472-6890/12/25. The authors measured cytokine levels in the blood of 201 subjects (110 with fibromyalgia). They concluded ‘The cytokine responses to mitogenic activators of PBMC isolated from patients with FM were significantly lower than those of …

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Extra Sensitive “Pain/Emotion” Perception

Nancy Ryan sent in this post. It has a number of threads to it. I picked the first idea as the title. These are things I haven’t  thought about much previously, and I found that the citations were interesting and enlightening. She writes: Maybe FM should be renamed “ESPP” for “Extra Sensitive “Pain/Emotion” Perception,” and …

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Fibromyalgia changes slightly, but importantly, over time—So what is Fibromyalgia?

Fibromyalgia’s officially been around for almost 25 years—if you link its birth to the 1990 American College of Rheumatology (ACR) criteria, and for more than 150 years if you consider that fibromyalgia and neurasthenia are the same entity in different dress and times.  It is not always clear what fibromyalgia is. There is Chronic Widespread …

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Fibromyalgia as a Trait (and a Continuum) Disorder

Because fibromyalgia is a symptom based disorder, rather than a disease, it ‘officially’ begins when a person satisfies fibromyalgia criteria and is diagnosed by a physician. Prior to the 2010 criteria, that meant satisfying the 1990 ACR fibromyalgia criteria and its requirement of the tender point examination. The 2010 criteria require only self-reported symptoms that …

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Fibromyalgia: Scientifically Dubious Arguments

At the end of his post, John Quintner identifies five ‘scientifically dubious arguments.’ To raise such issues is not in any way to disparage fibromyalgia or patients who suffer from pain. Rather, it raises specific questions about what we believe, how we write and think, and how we use or misuse evidence. What is the …

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Fibromyalgia ‘Patient’ Comments

When I first began to think about a blog I found widespread advice that all comments should be moderated. Moderated means that the blog editor (that’s me) will read the comments and decide whether they should be allowed. Despite filters, blogs get spam and ‘inappropriate’ comments that can’t be allowed. The blog was designed to …

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Travell, Simons and Cargo Cult Science

In an important article, Wally Smith writes about ‘Pseudoevidence-based medicine.’1 He defines it ‘as the practice of medicine based on falsehoods that are disseminated as truth. Falsehoods may result from corrupted evidence – evidence that has been suppressed, contrived from purposely biased science, or that has been manipulated and/or falsified, then published. Or falsehoods may …

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